Prof. Antonio M. Echavarren
Group Leader:
Antonio M. Echavarren
Administrative Support:
Sònia Gavaldà
Laboratory Engineer:
Imma Escofet
Postdoctoral Researchers:
Xiaoming Jie (until Jan.) / Cristina García Morales (until May) / Giuseppe Zuccarello (Jul. – Nov.) / Allegra Franchino / Leonardo Nannini / Franco Della Felice / Marc Montesinos / Rémi Blieck
PhD Students:
Giuseppe Zuccarello (until June) / Margherita Zanini (until Nov.) / Joan G. Mayans / Otilia Stoica / Ulysse Caniparoli / Mauro Mato / Helena Armengol / Alba H. Pérez / Inma Martín / Ana Arroyo / Eduardo García Padilla / Alex Martí / Gal·la Ogalla / Andrea Cataffo / Tania Medina / Isabel Arranz / Pablo Mora
Master Students:
Arnau Rodríguez Sugranyes / Matthias Peeters
Summary
The group of Prof. Echavarren focuses on the design of catalytic systems and the invention of a new organic synthesis methodology. The most important scientific contributions of the group have been in the field of homogenous gold catalysis, where they have established the mechanistic foundations that have guided the discovery of new transformations and have introduced gold catalysts to the scientific community. They have also demonstrated the usefulness of new synthetic methods in the context of the synthesis of complex molecules, both biologically relevant natural products and molecules of interest in materials science.
Publications
Assembly of Complex 1,4‐Cycloheptadienes by (4+3) Cycloaddition of Rhodium(II) and Gold(I) Non‐Acceptor Carbenes
Armengol-Relats, H.; Mato, M.; Echavarren, A. M.
Angew. Chem. Int. Ed. 2020
Iridium‐Catalyzed β‐Alkynylation of Aliphatic Oximes as Masked Carbonyl Compounds and Alcohols
Tan, E.; Zanini, M.; Echavarren, A. M.
Angew. Chem. Int. Ed. 2020, 59 (26), 10470-10473
Silver-Free Catalysis with Gold(I) Chloride Complexes
Franchino, A.; Montesinos-Magraner, M.; Echavarren, A. M.
Bull. Chem. Soc. Jpn. 2020
MORE PUBLICATIONS
On the Structure of Intermediates in Enyne Gold(I)‐Catalyzed Cyclizations: Formation of trans‐Fused Bicyclo[5.1.0]octanes as a Case Study
Escofet, I.; Armendol-Relats, H.; Bruss, H.; Besora, M.; Echavarren, A. M.
Chem.: Eur. J 2020, 26 (67), 15738-15745
Gold-Catalyzed Synthesis of Small Rings
Mato, M.; Franchino, A.; Garcı́a-Morales, C.; Echavarren, A. M.
Chem. Rev. 2020
Electronic decoupling of polyacenes from the underlying metal substrate by sp3 carbon atoms
Mohammed, M. S. G.; Colazzo, L.; Robles, R.; Dorel, R.; Echavarren, A. M.; Lorente, N.; de Oteyza, D. G.
Commun. Phys. 2020, 3, 159
Bridgehead Modifications of Englerin A Reduce TRPC4 Activity and Intravenous Toxicity but not Cell Growth Inhibition
Wu, Z.; Suppo, J. S.; Tumova, S.; Strope, J.; Bravo, F.; Moy, M.; Weinstein, E. S.; Peer, C. J.; Figg, W. D.; Chain, W. J.; Echavarren, A. M.; Beech, D. J.; Beutler, J. A.
ACS Med. Chem. Lett. 2020, 11 (9), 1711-1716
Photoredox-Assisted Gold-Catalyzed Arylative Alkoxycyclization of 1,6-Enynes
Mayans, J. G.; Suppo, J. S.; Echavarren, A. M.
Org. Lett. 2020, 22 (8), 3045–3049
Small Gold(I) and Gold(I)‐Silver(I) Clusters via C‐Si Auration
Pei, X. L.; Pereira, A.; Smirnova, E. S.; Echavarren, A. M.
Chem.: Eur. J 2020, 26 (32), 7309-7313
Buchwald‐Type Ligands on Gold(I) Catalysis
Zuccarello, G.; Zanini, M.; Echavarren, A. M.
Isr. J. Chem. 2020, 60 (3-4), 360-372
Synthesis of Trienes by Rhodium-Catalyzed Assembly and Disassembly of Non-Acceptor Cyclopropanes
Mato, M.; García-Morales, C.; Echavarren, A. M.
ACS Catal. 2020, 10 (6), 3564–3570
Acetylene as a Dicarbene Equivalent via Gold(I) Catalysis: Total Synthesis of Waitziacuminone in One Step
Scharnagel, D.; Escofet, I.; Armengol-Relats, H.; de Orbe, M. E.; Nepomuk Korber, J.; Echavarren, A. M.
Angew. Chem. Int. Ed. 2020, 59 (12), 4888-4891
Projects
Bioinspired Catalytic Metallofoldamers
ERC Advanced Grant | Ref: 385080
A new platform technology for the on-demand access to large acenes
ERC Proof of Concept | Ref: 837225
Química Organometàl·lica en Síntesi Orgànicas
AGAUR | Ref: 2017 SGR 1257
Theses Supervised
Imma Escofet
June 12th, 2020
Universitat Rovira i Virgili
‘Computational Mechanistic Studies in Gold(I) Catalysis and Design of New Chiral Ligands’
Giuseppe Zuccarello
June 22nd, 2020
Universitat Rovira i Virgili
‘Chiral Pyrrolidinyl-Biphenyl Phosphine Ligands in Gold(I) Catalysis’
Margherita Zanini
November 12th, 2020
Universitat Rovira i Virgili
‘Transition Metal-Catalyzed Reactions of Heteroatom-Substituted Alkynes’
Estefanía del Castillo
December 10th, 2020
Universitat Rovira i Virgili
‘Applications of the Hofmann-Löffler Reaction for C-H Functionalization in Total Synthesis’