Prof. Kilian Muñiz
Prof. Kilian Muñiz passed away on March 16th, 2020
Group Leader:
Kilian Muñiz, ICREA Professor
Administrative Support:
Sorania Jiménez
Postdoctoral Researchers:
Kang Chen (until Sep.)
PhD Students:
Anastasia Tkacheva (Until Mar. / Estefanía del Castillo Fernández (until Dec.) / Daniel Fermin Bafaluy Español (until Oct.) / Thomas Lionel Gerard Duhamel (until Nov.) / Èric Cots Fargas / Eleni Georgiou / Aliénor Céline Jeandin / Jiayu Zhang / Jixiang Ni
Summary
The group of Prof. Muñiz deals with the discovery of new chemical transformations that provide direct access to molecules that contain nitrogen, which are key in a variety of compounds of biological and pharmaceutical interest. They have designed new hypomorphic iodine monomeric reagents that incorporate unprecedented iodine nitrogen links, resulting in a new enantioselective diaminization methodology. In addition, the group works on the expansion of the concept of halide oxidation chemistry. This research resulted in a series of amine reactions of non-functionalized C-H links catalysed by halides, providing access to nitrogenous aliphatic heterocycles not previously available.
Publications
Kilian Muñiz (1970–2020)
Streuff, J.; Echavarren, A. M.; González, J. M.; Oestreich, M.; Gansäuer, A.; Barluenga, S.; Winssinger, N.
Angew. Chem. Int. Ed. 2020
Detection of the Elusive Nitrogen‐Centered Radicals from Catalytic Hofmann–Löffler Reactions
Bosnidou, A. E.; Duhamel, T.; Muñiz, K.
Eur. J. Org. Chem. 2020, 2020 (40), 6361-6365
An Iodine‐Catalysis Approach to C(sp3)‐H Fluorination with Nucleophilic Fluorine
Bafaluy, D.; Georgieva, Z.; Muñiz, K.
COVER Angew. Chem. Int. Ed. 2020, 59 (34), 14241-14245
MORE PUBLICATIONS
Projects
HalOx
Diseño de sistemas de oxidación basados en haluros para la formación de enlaces C-N
Ministerio | Ref: CTQ2017-88496-R
Proyectos I+D – Retos
CHAOS
C-H Activation in Organic Synthesis
COST-European Cooperation in Science and Technology | Ref: EU Cost Action 15106
Theses Supervised
Daniel Bafaluy
October 2nd, 2020
Universitat Rovira i Virgili
«New Strategies for C(sp3)-H Functionalization»
Thomas Duhamel
October 2nd, 2020
Universitat Rovira i Virgili
«Design of New C(sp3)-H Functionalization Through Halogen Catalysis»
Estefanía del Castillo
December 10th, 2020
Universitat Rovira i Virgili
«Applications of the Hofmann-Löffler Reaction for C-H Functionalization in Total Synthesis»
Anastasia Tkacheva
December 14th, 2020
Universitat Rovira i Virgili
«Complex Anionic Halide Reagents as a Novel Useful Compound Class for Direct C-H Functionalizations: Studies Towards Aromatic Amination Reactions»
Features
Lightning the way for a new fluorination methodology
https://www.iciq.org/lighting-the-way-for-a-new-fluorination-methodology/