Prof. Kilian Muñiz

Catalysis

Prof. Kilian Muñiz passed away on March 16th, 2020

Group Leader:

Kilian Muñiz, ICREA Professor

Administrative Support:

Sorania Jiménez

Postdoctoral Researchers:

Kang Chen (until Sep.)

PhD Students:

Anastasia Tkacheva (Until Mar. / Estefanía del Castillo Fernández (until Dec.) / Daniel Fermin Bafaluy Español (until Oct.) / Thomas Lionel Gerard Duhamel (until Nov.) / Èric Cots Fargas / Eleni Georgiou / Aliénor Céline Jeandin / Jiayu Zhang / Jixiang Ni

Summary

The group of Prof. Muñiz deals with the discovery of new chemical transformations that provide direct access to molecules that contain nitrogen, which are key in a variety of compounds of biological and pharmaceutical interest. They have designed new hypomorphic iodine monomeric reagents that incorporate unprecedented iodine nitrogen links, resulting in a new enantioselective diaminization methodology. In addition, the group works on the expansion of the concept of halide oxidation chemistry. This research resulted in a series of amine reactions of non-functionalized C-H links catalysed by halides, providing access to nitrogenous aliphatic heterocycles not previously available.

Publications

Kilian Muñiz (1970–2020)
Streuff, J.; Echavarren, A. M.; González, J. M.; Oestreich, M.; Gansäuer, A.; Barluenga, S.; Winssinger, N.
Angew. Chem. Int. Ed. 2020

Detection of the Elusive Nitrogen‐Centered Radicals from Catalytic Hofmann–Löffler Reactions
Bosnidou, A. E.; Duhamel, T.; Muñiz, K.
Eur. J. Org. Chem. 2020, 2020 (40), 6361-6365

An Iodine‐Catalysis Approach to C(sp3)‐H Fluorination with Nucleophilic Fluorine
Bafaluy, D.; Georgieva, Z.; Muñiz, K.
COVER Angew. Chem. Int. Ed. 2020, 59 (34), 14241-14245

MORE PUBLICATIONS

Projects

HalOx
Diseño de sistemas de oxidación basados en haluros para la formación de enlaces C-N
Ministerio | Ref: CTQ2017-88496-R
Proyectos I+D – Retos

CHAOS
C-H Activation in Organic Synthesis
COST-European Cooperation in Science and Technology | Ref: EU Cost Action 15106

 

Theses Supervised

Daniel Bafaluy
October 2nd, 2020
Universitat Rovira i Virgili
New Strategies for C(sp3)-H Functionalization”

Thomas Duhamel
October 2nd, 2020
Universitat Rovira i Virgili
Design of New C(sp3)-H Functionalization Through Halogen Catalysis”

Estefanía del Castillo
December 10th, 2020
Universitat Rovira i Virgili
Applications of the Hofmann-Löffler Reaction for C-H Functionalization in Total Synthesis”

Anastasia Tkacheva
December 14th, 2020
Universitat Rovira i Virgili
Complex Anionic Halide Reagents as a Novel Useful Compound Class for Direct C-H Functionalizations: Studies Towards Aromatic Amination Reactions”

 

Features

Lightning the way for a new fluorination methodology
https://www.iciq.org/lighting-the-way-for-a-new-fluorination-methodology/